Article

The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization

2024-07-23

Abstract excerpt

<h4>Statement of Significance</h4> We showed that loss of the orphan G protein-coupled receptor GPR52 in human breast cell lines leads to increased cell clustering, hybrid/partial EMT, and increased tumor burden in zebrafish. <h4>Background</h4> G protein-coupled receptors (GPCRs) are the largest class of membrane-bound receptors that transmit critical signals from extracellular to intracellular spaces. Transcri...

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Literature Corpus work: 93ea0c35-6f31-5827-862a-d460dd30f566
DOI: 10.1101/2024.07.22.604482

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