Back to search

Article

PROTEOME-WIDE ANALYSIS OF CD8+ T CELL RESPONSES TO EBV REVEALS DIFFERENCES BETWEEN PRIMARY AND PERSISTENT INFECTION

2018-05-21

Abstract excerpt

<h4>ABSTRACT (286 words)</h4> Human herpesviruses are antigenically rich agents that induce strong CD8+T cell responses in primary infection yet persist for life, continually challenging T cell memory through recurrent lytic replication and potentially influencing the spectrum of antigen-specific responses. Here we describe the first lytic proteome-wide analysis of CD8+ T cell responses to the Epstein-Barr gamma1...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
93e1a768-ba31-5370-bef5-4a1ad126ff8e
DOI
10.1101/327312
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PROTEOME-WIDE ANALYSIS OF CD8+ T CELL RESPONSES TO EBV REVEALS DIFFERENCES BETWEEN PRIMARY AND PERSISTENT INFECTIONDOI 10.1101/327312
Proteome-wide analysis of CD8+ T cell responses to EBV reveals differences between primary and persistent infectionSemantic proximity
Epitope-specific Evolution of Human CD8<b>+</b> T Cell Responses from Primary to Persistent Phases of Epstein-Barr Virus InfectionSemantic proximity
Ex Vivo Profiling of CD8<sup>+</sup>-T-Cell Responses to Human Cytomegalovirus Reveals Broad and Multispecific Reactivities in Healthy Virus CarriersSemantic proximity
A high-resolution, unbiased analysis of the cellular immune response to Epstein-Barr virusSemantic proximity
Immediate Early and Early Lytic Cycle Proteins Are Frequent Targets of the Epstein-Barr Virus–induced Cytotoxic T Cell ResponseSemantic proximity
EBV INFECTION OUTCOMES DETERMINED BY MONOCYTE AND T <sub>REG</sub> -DRIVEN IMMUNE DYNAMICS IN AN EX VIVO PBMC MODELSemantic proximity
MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.Semantic proximity
Differential Immunogenicity of Epstein-Barr Virus Latent-Cycle Proteins for Human CD4+T-Helper 1 ResponsesSemantic proximity
CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term SurvivalSemantic proximity
Cytotoxic CD4+ T Cell Responses to EBV Contrast with CD8 Responses in Breadth of Lytic Cycle Antigen Choice and in Lytic Cycle RecognitionSemantic proximity
Single-cell transcriptomic and TCR analysis of human Cytomegalovirus (hCMV)-specific memory T cells reveals effector and pre-effectors of CD8 <sup>+</sup> - and CD4 <sup>+</sup> -cytotoxic T cellsSemantic proximity
A high-resolution, unbiased analysis of the cellular immune response to Epstein-Barr virusSemantic proximity
Select a neighboring publication to make it the new centre.