Article
Comprehensive Metabolic Phenotyping Refines Cardiovascular Risk in Young Adults.
Circulation - 1 Dec 2020
Murthy Venkatesh L, Reis Jared P, Pico Alexander R, Kitchen Robert, Lima Joao A C, Lloyd-Jones Donald, Allen Norrina B, Carnethon Mercedes, Lewis Gregory D, Nayor Matthew, Vasan Ramachandran S, Freedman Jane E, Clish Clary B, Shah Ravi V
Abstract excerpt
BACKGROUND: Whereas cardiovascular disease (CVD) metrics define risk in individuals >40 years of age, the earliest lesions of CVD appear well before this age. Despite the role of metabolism in CVD antecedents, studies in younger, biracial populations to define precise metabolic risk phenotypes are lacking. METHODS: We studied 2330 White and Black young adults (mean age, 32 years; 45% Black) in the CARDIA study...
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