Article
TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America - 7 Mar 2017
Nishimura Marc T, Anderson Ryan G, Cherkis Karen A, Law Terry F, Liu Qingli L, Machius Mischa, Nimchuk Zachary L, Yang Li, Chung Eui-Hwan, El Kasmi Farid, Hyunh Michael, Osborne Nishimura Erin, Sondek John E, Dangl Jeffery L
Abstract excerpt
Detection of pathogens by plants is mediated by intracellular nucleotide-binding site leucine-rich repeat (NLR) receptor proteins. NLR proteins are defined by their stereotypical multidomain structure: an N-terminal Toll-interleukin receptor (TIR) or coiled-coil (CC) domain, a central nucleotide-binding (NB) domain, and a C-terminal leucine-rich repeat (LRR). The plant innate immune system contains a limited NLR...
Topics
- Arabidopsis
- Arabidopsis Proteins
- Binding Sites
- Cell Death
- Crystallography, X-Ray
- Erwinia
- Gene Expression Regulation, Plant
- Host-Pathogen Interactions
- Models, Molecular