Article

PncA from bacteria improves diet-induced NAFLD by enabling the transition from NAM to NA in mice

2021-12-04

Abstract excerpt

Nicotinamide adenine dinucleotide (NAD + ) is crucial for energy metabolism, oxidative stress, DNA damage repair, longevity regulation, and several signaling processes. To date, three NAD + synthesis pathways have been found in microbiota and hosts, but the potential relationship between gut microbiota and their hosts in regulating NAD + homeostasis remains unknown. Here, we show that an analog of the first-lin...

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Literature Corpus work: 93303f0b-156d-5fea-980d-e634d55ffa63
DOI: 10.1101/2021.12.04.471202

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