Article

Andes virus genome mutations that are likely associated with animal-model attenuation and human person-to-person transmission

2023-01-20

Abstract excerpt

<h4>STRUCTURED ABSTRACT</h4> We performed whole-genome sequencing with bait-enrichment techniques to analyze Andes virus (ANDV), a cause of human hantavirus pulmonary syndrome. We used cryopreserved lung tissues from a naturally infected long-tailed colilargo; early, intermediate, and late cell-culture passages of an ANDV isolate from that animal; and lung tissues from golden hamsters experimentally exposed to th...

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Literature Corpus work: 931006cd-4536-56ca-b2e2-dc08bfd817e1
DOI: 10.1101/2023.01.18.524667

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