Article

SARS-CoV-2 evolution in animals suggests mechanisms for rapid variant selection

2021-03-08

Abstract excerpt

SARS-CoV-2 spillback from humans into domestic and wild animals has been well-documented. We compared variants of cell culture-expanded SARS-CoV-2 inoculum and virus recovered from four species following experimental exposure. Five nonsynonymous changes in nsp12, S, N and M genes were near fixation in the inoculum, but reverted to wild-type sequences in RNA recovered from dogs, cats and hamsters within 1-3 days po...

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Literature Corpus work: 9bc216d7-2bfc-5a75-acf6-96f9c6c4450e
DOI: 10.1101/2021.03.05.434135

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