Article

Unlocking opioid neuropeptide dynamics with genetically-encoded biosensors

2023-05-30

Abstract excerpt

<title>Abstract</title> <p>Neuropeptides are ubiquitous in the nervous system. Research into neuropeptides has been limited by a lack of experimental tools that allow for the precise dissection of their complex and diverse dynamics in a circuit-specific manner. Opioid peptides comprise a clinically relevant family that modulates pain, reward, and aversion. To illuminate the spatiotemporal dynamics of endogenous o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 92bd20dd-468f-587d-8dc2-01d1d4b832a4
DOI: 10.21203/rs.3.rs-2871083/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Unlocking opioid neuropeptide dynamics with genetically-encoded biosensorsDOI 10.21203/rs.3.rs-2871083/v1Read

A genetically encoded biosensor reveals location bias of opioid drug actionSemantic proximity Read

Correspondence of fentanyl brain pharmacokinetics and behavior measured via engineering opioids biosensors and computational ethologySemantic proximity Read

Imaging Striatal Dopamine Release Using a Non-Genetically Encoded Near-Infrared Fluorescent Catecholamine NanosensorSemantic proximity Read

Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell typesSemantic proximity Read

GESIAP: A Versatile Genetically Encoded Sensor-based Image Analysis ProgramSemantic proximity Read

Fiber-based Probes for Electrophysiology, Photometry, Optical and Electrical Stimulation, Drug Delivery, and Fast-Scan Cyclic Voltammetry In VivoSemantic proximity Read

Hydrogen-bonded organic framework nanotransducers enabled sono-optogenetics for Parkinsonian ratsSemantic proximity Read

Development of a genetically-encoded oxytocin sensorSemantic proximity Read

A Comprehensive Optogenetic Pharmacology Toolkit for In Vivo Control of GABA(A) Receptors and Synaptic Inhibition.Semantic proximity Read

Optogenetic Control of Mammalian Ion Channels with Chemical Photoswitches.Semantic proximity Read

Parabrachial CGRP Neurons Regulate Opioid ReinforcementSemantic proximity Read

Minimally invasive delivery of peptides to the spinal cord for behavior modulationSemantic proximity Read