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Hydrogen-bonded organic framework nanotransducers enabled sono-optogenetics for Parkinsonian rats

2025-01-04

Abstract excerpt

Cell-type-specific activation of parvalbumin (PV)-expressing neurons in the external globus pallidus (GPe) through optogenetics has shown promise in facilitating long-lasting movement dysfunction recovery in mice with Parkinson’s disease. However, its translational potential is hindered by adverse effects stemming from the invasive implantation of optical fibers into the brain. In this study, we have developed a n...

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Literature Corpus work
302be4ab-e94f-5b22-8ba1-009f45ec91a1
DOI
10.1101/2025.01.03.631271
Open publication

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Hydrogen-bonded organic framework nanotransducers enabled sono-optogenetics for Parkinsonian ratsDOI 10.1101/2025.01.03.631271
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