Article

Alnustone inhibits Streptococcus pneumoniae virulence by targeting pneumolysin and sortase A

2022-03-07

Abstract excerpt

Streptococcus pneumoniae (S. pneumoniae) is a significant Gram-positive opportunistic pathogen responsible for a variety of lethal infections. This bacterium accounts for more deaths from diseases than any other single pathogen worldwide. Distinctively, these symptoms arise despite effective antibiotic therapy. This study unveiled a novel mechanism of resistance to S. pneumoniae infection by targeting pneumolysin...

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Literature Corpus work: 92adc1a3-9682-5aa8-afdb-9b795f07c308
DOI: 10.1101/2022.03.07.483358

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