Article

Parental-fetal interplay of immune genes leads to intrauterine growth restriction

2021-03-28

Abstract excerpt

Intrauterine growth restriction (IUGR) of fetuses affects 5-10% of pregnancies and is associated with perinatal morbidity, mortality and long-term health issues. Understanding genetic predisposition to IUGR is challenging, owing to extensive gene polymorphisms, linkage disequilibrium, and maternal and paternal influence. Here, we demonstrate that the inhibitory receptor, KIR2DL1, expressed on maternal uterine natu...

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Identifiers and source

Literature Corpus work: 9286043e-5774-5886-8642-6a1e6bba4c34
DOI: 10.1101/2021.03.26.437292

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