Article

Reconstructing the human first trimester fetal–maternal interface using single cell transcriptomics

2018-09-29

Abstract excerpt

<h4>Summary</h4> During the early weeks of human pregnancy, the fetal placenta implants into the uterine mucosa (decidua) where placental trophoblast cells intermingle and communicate with maternal cells. Here, we profile transcriptomes of ∼50,000 single cells from this unique microenvironment, sampling matched first trimester maternal blood and decidua, and fetal cells from the placenta itself. We define the cel...

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Literature Corpus work: b1a6f62a-ac34-5456-a051-70cc3de2cea7
DOI: 10.1101/429589

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