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Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade

29 Jul 2022

Abstract excerpt

Fetal growth restriction (FGR) affects 5-10% of pregnancies, and can have serious consequences for both mother and child. Prevention and treatment are limited because FGR pathogenesis is poorly understood. Genetic studies implicate KIR and HLA genes in FGR, however, linkage disequilibrium, genetic influence from both parents, and challenges with investigating human pregnancies make the risk alleles and their...

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PMID: 35906236
DOI: 10.1038/s41467-022-32171-w

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