Article

Platelet-rich plasma-derived exosomes accelerate the healing of diabetic foot ulcers by promoting macrophage polarization to the M2 phenotype

2025-03-27

Abstract excerpt

<title>Abstract</title> <p>Diabetic foot ulcers (DFUs) impose a significant clinical and socioeconomic burden on patients and healthcare systems. Although platelet-rich plasma (PRP) and platelet-rich plasma-derived exosomes (PRP-Exos) have emerged as promising therapeutic agents in tissue regeneration, the mechanisms underlying the immunomodulatory effects of PRP and PRP-Exos—particularly their role in macrophage...

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Literature Corpus work: 925cf88f-7c56-5b7c-a15a-1b2b7cc3c6a6
DOI: 10.21203/rs.3.rs-5945926/v1

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