Article

Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection.

2022-11-22

Abstract excerpt

<title>Abstract</title> <p>Epithelial plasticity has been suggested in lungs of mice following genetic depletion of stem cells but is of unknown physiological relevance. Viral infection and chronic lung disease share similar pathological features of stem cell loss in alveoli, basal cell (BC) hyperplasia in small airways, and innate immune activation, that contribute to epithelial remodeling and loss of lung funct...

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Literature Corpus work: 6e940bae-269b-5bfa-ad48-bae1a26d6e90
DOI: 10.21203/rs.3.rs-2203831/v1

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