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Article

Inflammation resolution and specialized pro-resolving lipid mediators in chronic rhinosinusitis

1 Jul 2023

Abstract excerpt

INTRODUCTION: In chronic rhinosinusitis (CRS), a complex pathophysiology results from varied pro-inflammatory stimuli but is consistently characterized by classic cellular, molecular, and microbial alterations. Normally, endogenous specialized pro-resolving mediators (SPM) actively promote resolution of inflammation through numerous pathways, including those involved in host antimicrobial defense. However, these...

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PMID: 37392068
DOI: 10.1080/1744666x.2023.2232554

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