Article

Developing novel therapeutic strategies for targeting the p53 pathway in renal cell carcinoma

2014-01-01

Abstract excerpt

Renal cell carcinoma (RCC) is a notoriously difficult cancer to treat. RCC has an unpredictable course, is radio- and chemo-resistant and survival in response to treatment with current therapies for the metastatic disease is generally very poor. This underscores the necessity for novel therapeutics for this condition. The tumour suppressor p53 is rarely mutated in RCC and up-regulation of p53 and its negative regu...

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Literature Corpus work: 91ebcbb8-017b-5a6a-9061-35a7ac5bdfb2
DOI: 10.17638/00018973

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