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Disease specific alterations in the olfactory mucosa of patients with Alzheimer’s disease

2020-11-24

Abstract excerpt

<h4>ABSTRACT</h4> Olfactory dysfunction manifests early in several neurodegenerative disorders. Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. However, it is unclear how this tissue reflects key neurodegenerative features in Alzheimer’s disease. Here we report that Alzheimer’s disease olfactory mucosal cells obtained from live individuals secrete toxic amyloid-beta. We det...

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Literature Corpus work
91db4bd5-6cb5-5fb8-b2ae-ce8aa1160753
DOI
10.1101/2020.11.24.395947
Open publication

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Disease specific alterations in the olfactory mucosa of patients with Alzheimer’s diseaseDOI 10.1101/2020.11.24.395947
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