Article

A pro-endocrine pancreatic transcriptional program established during development is retained in human gallbladder epithelial cells

2021-03-02

Abstract excerpt

<h4>Objective</h4> Pancreatic islet β-cells are factories for insulin production; however ectopic expression of insulin is also well recognized. The gallbladder is a next-door neighbour to the developing pancreas. Here, we wanted to understand if gallbladders contain functional insulin-producing cells. <h4>Design</h4> We compared developing and adult mouse as well as human gallbladder epithelial cells and islets...

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Literature Corpus work: 9190f060-2eaa-5a55-a99c-888b5d0070b5
DOI: 10.1101/2021.03.02.433636

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