Article

Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins

2021-10-13

Abstract excerpt

Sexual reproduction consists of genome reduction by meiosis and subsequent gamete fusion. Presence of meiotic genes in prokaryotes suggests that DNA repair mechanisms evolved toward meiotic recombination; however, fusogenic proteins resembling those found in eukaryotes were not identified in prokaryotes. Here, we identify archaeal proteins that are homologs of fusexins, a superfamily of fusogens that mediate eukar...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 916e6146-22ec-5155-8641-8258309e5917
DOI: 10.1101/2021.10.13.464100

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteinsDOI 10.1101/2021.10.13.464100Read

Eukaryotic fertilization and gamete fusion at a glanceSemantic proximity Read

<i>Arabidopsis</i> HAP2/GCS1 is a gamete fusion protein homologous to somatic and viral fusogensSemantic proximity Read

SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteinsSemantic proximity Read

Structure-Function Studies Link Class II Viral Fusogens with the Ancestral Gamete Fusion Protein HAP2.Semantic proximity Read

A conserved filamentous assembly underlies the structure of the meiotic chromosome axis.Semantic proximity Read

Evolutionary and functional dynamics of chimeric pseudogenes (φgenes)Semantic proximity Read

PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex.Semantic proximity Read

Protist and Fungal Metaxin-like Proteins: Relationship to Vertebrate Metaxins that Function in Protein Import into MitochondriaSemantic proximity Read

Homeodomain protein Sxi1α independently controls cell-cell fusion and gene expression during sexual reproduction in <i>Cryptococcus deneoformans</i>Semantic proximity Read

Functional constraints of <i>wtf</i> killer meiotic driversSemantic proximity Read

A paralog of Pcc1 is the fifth core subunit of KEOPS complex in ArchaeaSemantic proximity Read

Asgard ESCRT-III and VPS4 reveal evolutionary conserved chromatin binding properties of the ESCRT machinerySemantic proximity Read