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Homeodomain protein Sxi1α independently controls cell-cell fusion and gene expression during sexual reproduction in <i>Cryptococcus deneoformans</i>

2025-02-14

Abstract excerpt

Sex-specific homeodomain (HD) proteins are key regulators of cell identity and sexual development in fungi, typically functioning as heterodimers to govern transcription. In the human fungal pathogens Cryptococcus neoformans and Cryptococcus deneoformans , the HD proteins Sxi1α and Sxi2 a (Sex-inducer 1α and 2 a ) have been characterized as interacting components that play critical roles in sexual development...

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Literature Corpus work
ab593c50-18c2-5d26-8d8d-3f11dc144466
DOI
10.1101/2025.02.11.637763
Open publication

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