Article

<i>Arabidopsis</i> HAP2/GCS1 is a gamete fusion protein homologous to somatic and viral fusogens

2016-12-31

Abstract excerpt

Cell-cell fusion is inherent to any form of sexual reproduction. Loss of HAPLESS 2/GENERATIVE CELL SPECIFIC 1 (HAP2/GCS1) proteins results in gamete fusion failure in different organisms but their exact role is unclear. Here we show that Arabidopsis HAP2/GCS1 expression in mammalian cells is sufficient to promote cell-cell fusion. Hemifusion and complete fusion depend on HAP2/GCS1 presence in both fusing cells. F...

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Literature Corpus work: 035bc802-11f7-55ba-be1e-a41647727e91
DOI: 10.1101/097568

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