Article

DHFR silencing effects on biological behaviour of ovarian carcinoma cells in vitro

2019-12-23

Abstract excerpt

<title>Abstract</title> <p>Background: Dyhidrofolate reductase (DHFR) is involved in the DNA synthesis and is expressed highly in platinum resistant ovarian carcinoma tissue . The relationship between DHFR gene and platinum drug resistance in ovarian carcinoma (OC) is still unclear. <h4>Methods:</h4> To design targeting hairpin siRNA of DHFR gene, and constructed lentiviral vector carrying DHFR gene, then though...

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Literature Corpus work: 915ce74d-f0fe-596f-9729-b71f37deaa7a
DOI: 10.21203/rs.2.19595/v1

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