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Clinicopathological and functional significance of XRCC1 expression in ovarian cancer

6 Dec 2012

Abstract excerpt

X-ray repair cross-complementing gene 1 (XRCC1) is essential for DNA base excision repair, single strand break repair and nucleotide excision repair. We investigated clinicopathological and functional significance of XRCC1 expression in ovarian cancers. XRCC1 protein expression was evaluated in 195 consecutive human ovarian cancers and correlated with clinicopathological variables and survival outcomes....

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DNA Repair Mechanisms
Ovarian cancer diagnosis and treatment
PARP inhibition in cancer therapy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23225521
DOI: 10.1002/ijc.27980

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