Article

The Fontan EV Score: A Circulating Extracellular Vesicle-Based Risk Stratification Tool for Fontan-Associated Liver Disease

2026-08-04

Abstract excerpt

<h4>Background</h4> Fontan-associated liver disease (FALD) is a universal complication of the Fontan palliation characterized by chronic congestion and progressive hepatic fibrosis. Current diagnostics rely on invasive biopsies or non-specific biochemical and imaging biomarkers that fail to capture early fibrogenesis, creating a critical need for non-invasive biomarkers to stratify disease severity. <h4>Methods</...

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Literature Corpus work: 914ed52c-0fcb-52d9-8701-5acbf35612bf
DOI: 10.64898/2026.07.31.742169

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