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Article

Clinically Interpretable Extracellular Vesicle Gene Model for Non-Invasive Liver Cancer Diagnosis

2025-12-19

Abstract excerpt

<title>Abstract</title> <p>Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide, underscoring the need for early non-invasive diagnostics. This study developed an interpretable model using extracellular vesicle (EV)-derived RNA signatures from exoRBase 2.0. Six machine learning algorithms were compared, with the Deep Neural Network (DNN) achieving superior performance (AUC = 0.8877). Ten diag...

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Literature Corpus work
496a130f-1207-5ef0-a65b-b477693f0488
DOI
10.21203/rs.3.rs-8217267/v1
Open publication

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Clinically Interpretable Extracellular Vesicle Gene Model for Non-Invasive Liver Cancer DiagnosisDOI 10.21203/rs.3.rs-8217267/v1
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