Article

ETS-guided iPSC-endothelial models recapitulate malaria pathogenesis

2025-07-02

Abstract excerpt

The sequestration of the malaria parasite Plasmodium falciparum in the microvasculature is a major driver of severe malaria, but its pathogenic mechanisms still remain unknown. Advancements in induced pluripotent stem cell (iPSC) technologies offer unique opportunities to study parasite interactions with blood vessels in a well-defined host environment. However, endothelial iPSC-differentiation methods often resu...

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Literature Corpus work: 91489a39-7e94-5ba8-bde1-940f004d9b4b
DOI: 10.1101/2025.07.01.662615

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