Article

Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

2020-03-03

Abstract excerpt

<h4>ABSTRACT</h4> Human induced pluripotent stem cell (h-iPSC)–derived endothelial cells (h-iECs) have become a valuable tool in regenerative medicine. However, current differentiation protocols remain inefficient and lack reliability. Here, we describe a method for rapid, consistent, and highly efficient generation of h-iECs. The protocol entails the delivery of modified mRNA encoding the transcription factor E...

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Literature Corpus work: 26ba3732-887b-5b05-bb94-9088f3a1e53c
DOI: 10.1101/2020.03.02.973289

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