Article

Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis

2020-04-13

Abstract excerpt

Erastin, which has been initially identified as a synthetic lethal compound against cancer expressing an RAS oncogene, inhibits cystine/glutamate antiporters and causes ferroptic cell death in various cell types, including therapy-resistant mesenchymal cancer cells. However, despite recent emerging evidence for the mechanisms underlying ferroptosis, molecular biomarkers associated with erastin-dependent ferroptosi...

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Literature Corpus work: 95cf5698-f306-511f-8a32-ebe7bb9a8c44
DOI: 10.1101/2020.04.13.038430

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