Article

Hot spots and labyrinths: Why neuromodulation devices for episodic migraine should be personalized

2014-09-26

Abstract excerpt

Stimulation protocols for medical devices should be rationally designed. For episodic migraine with aura we outline model-based design strategies towards preventive and acute therapies using stereotactic neuromodulation. To this end, we regard a localized spreading depression (SD) wave segment as a central element in migraine pathophysiology. To describe nucleation and propagation features of the SD wave segment,...

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Literature Corpus work: 912e4fe8-529c-563e-a32b-c7fe7223878a
DOI: 10.7287/peerj.preprints.515v1

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