Article

Formation, stability, and competition in dendritic proto-spines

2026-01-09

Abstract excerpt

Over 80 % of excitatory synapses in the mammalian brain terminate on dendritic spines, which support key functions of memory storage and computation. Despite the neurodevelopmental and computational implications of spine formation, little is known about the interplay of physical and chemical signaling mechanisms that govern spine initiation. We developed a physics-based model for the formation, stability, and plac...

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Literature Corpus work: 0d7a3180-a711-50d2-8b6f-f6e910160a44
DOI: 10.64898/2026.01.09.697842

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