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Article

Network crosstalk dynamically changes during neutrophil polarization.

Cell - 25 May 2012

Ku Chin-Jen, Wang Yanqin, Weiner Orion D, Altschuler Steven J, Wu Lani F

Abstract excerpt

How complex signaling networks shape highly coordinated, multistep cellular responses is poorly understood. Here, we made use of a network-perturbation approach to investigate causal influences, or "crosstalk," among signaling modules involved in the cytoskeletal response of neutrophils to chemoattractant. We quantified the intensity and polarity of cytoskeletal marker proteins over time to characterize...

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Identifiers

PMID: 22632971
DOI: 10.1016/j.cell.2012.03.044
PMCID: PMC3614011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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