Article
Network crosstalk dynamically changes during neutrophil polarization.
Cell - 25 May 2012
Ku Chin-Jen, Wang Yanqin, Weiner Orion D, Altschuler Steven J, Wu Lani F
Abstract excerpt
How complex signaling networks shape highly coordinated, multistep cellular responses is poorly understood. Here, we made use of a network-perturbation approach to investigate causal influences, or "crosstalk," among signaling modules involved in the cytoskeletal response of neutrophils to chemoa...
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