Article

Genome-Wide Association Study of Genetic Variants Associated with Lower Extremity Amputation Risk in Peripheral Artery Disease

2025-12-20

Abstract excerpt

Peripheral artery disease (PAD) is a global health burden affecting over 200 million individuals and is frequently complicated by limb-threatening ischemia, leading to major amputations. Despite known clinical risk factors, the genetic basis underlying amputation risk in PAD remains poorly defined. In this study, we performed a multi-pronged genome-wide association study (GWAS) to identify genetic variants associa...

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Literature Corpus work: 90b49dee-3c60-5aca-a3d5-3fd6fb045976
DOI: 10.64898/2025.12.17.25342479

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