Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide Association Study of Genetic Variants Associated with Lower Extremity Amputation Risk in Peripheral Artery Disease.

International journal of molecular sciences - 10 Apr 2026

Korutla Rajashekar, Garg Tanisha, Wilczek Michael P, Ross Elsie G, Amal Saeed

Abstract excerpt

Peripheral artery disease (PAD) is a global health burden affecting over 200 million individuals and is frequently complicated by limb-threatening ischemia, leading to major amputations. Despite known clinical risk factors, the genetic basis underlying amputation risk in PAD remains poorly defined. In this study, we performed a multi-pronged genome-wide association study (GWAS) to identify genetic variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genome-Wide Association Study

Share to Lower Extremity

Share to Peripheral Arterial Disease

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 42074049
DOI: 10.3390/ijms27083405
PMCID: PMC13115880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Association Study of Genetic Variants Associated with Lower Extremity Amputation Risk in Peripheral Artery Disease.PMID 42074049Read ↗

Genome-Wide Association Study of Genetic Variants Associated with Lower Extremity Amputation Risk in Peripheral Artery DiseaseSemantic proximity Read ↗

Genome-Wide Association Study of Genetic Variants Associated with Lower Extremity Amputation Risk in Peripheral Artery DiseaseSemantic proximity Read ↗

The Genetic Architecture of the Etiology of Lower Extremity Peripheral Artery Disease: Current Knowledge and Future Challenges in the Era of Genomic Medicine.Semantic proximity Read ↗

Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology.Semantic proximity Read ↗

[Advances in research on the genetics of peripheral arterial disease].Semantic proximity Read ↗

Genome- and Transcriptome-wide association meta-analysis reveals new insights into genes affecting coronary and peripheral artery diseaseSemantic proximity Read ↗

A field synopsis and meta-analysis of genetic association studies in peripheral arterial disease: The CUMAGAS-PAD database.Semantic proximity Read ↗

The genetic basis of peripheral arterial disease: current knowledge, challenges, and future directions.Semantic proximity Read ↗

Peripheral Arterial Disease Genetics: Progress to Date and Challenges Ahead.Semantic proximity Read ↗

Unraveling shared risk factors for diabetic foot ulcer: a comprehensive Mendelian randomization analysisSemantic proximity Read ↗

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.Semantic proximity Read ↗

The role of biomarkers and genetics in peripheral arterial disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.