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Integration of bulk and single-cell RNA-seq data identifies a cellular senescence-related prognostic signature in liver hepatocellular carcinoma

2026-04-23

Abstract excerpt

<title>Abstract</title> <p>Liver Hepatocellular carcinoma (LIHC) is a highly heterogeneous malignancy with poor prognosis, underscoring the urgent need for reliable biomarkers and therapeutic targets. Cellular senescence plays a dual role in tumor progression, yet the landscape of cellular senescence-related genes (CSRGs) in LIHC remains incompletely characterized. In this study, we curated 167 CSRGs from the Gen...

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Literature Corpus work
90a4d5b2-7fa5-56c2-8adf-f3a2c21d2ea2
DOI
10.21203/rs.3.rs-9198475/v1
Open publication

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Integration of bulk and single-cell RNA-seq data identifies a cellular senescence-related prognostic signature in liver hepatocellular carcinomaDOI 10.21203/rs.3.rs-9198475/v1
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