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Characterization of cellular senescence patterns predicts the prognosis and therapeutic response of hepatocellular carcinoma

16 Dec 2022

Abstract excerpt

Background: Hepatocellular carcinoma (HCC) is a prevalent malignancy with a high mortality rate. Cellular senescence, an irreversible state of cell cycle arrest, plays a paradoxical role in cancer progression. Here, we aimed to identify Hepatocellular carcinoma subtypes by cellular senescence-related genes (CSGs) and to construct a cellular senescence-related gene subtype predictor as well as a novel prognostic...

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PMID: 36589233
DOI: 10.3389/fmolb.2022.1100285

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