Article

FAP+ cells restrict antibody drug delivery and promote an immunosuppressive environment in head and neck squamous cell carcinoma.

2025-03-25

Abstract excerpt

<title>Abstract</title> <p>Background Antibody-based therapies (such as anti-EGFR and anti-PD1/L1 agents) have altered the landscape of cancer treatment to improve patient outcomes in formerly unresponsive tumor types. However, this robust response is not ubiquitous for all patients or cancer subtypes. Head and neck squamous cell carcinoma continues to have reduced response in many patient populations regardless...

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Literature Corpus work: 905ed055-cc56-5e4f-993a-4e8faf92ca82
DOI: 10.21203/rs.3.rs-6228925/v1

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