Article

Neurotransmission Sex Dichotomy in the Rat Hypothalamic Paraventricular Nucleus in Health and Infantile Spasm Model

2025-03-27

Abstract excerpt

We profiled the gene expressions in hypothalamic paraventricular nuclei of 12 male and 12 female pups from a standard rat model of infantile spasms to determine the sex dichotomy of the neurotransmission genomic fabrics. Infantile spasms were triggered in rat pups prenatally primed with two doses of betamethasone followed by postnatal repeated administration of N-methyl-D-aspartic acid to induce spasms. Publicly a...

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Literature Corpus work: 905dc4b4-3e73-5f5d-ac7c-8c24c2664fbe
DOI: 10.20944/preprints202503.2046.v1

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