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Article

Genetic and biologic classification of infantile spasms.

Pediatric neurology - 1 Dec 2011

Paciorkowski Alex R, Thio Liu Lin, Dobyns William B

Abstract excerpt

Infantile spasms constitute an age-dependent epilepsy, highly associated with cognitive impairment, autism, and movement disorders. Previous classification systems focused on a distinction between symptomatic and cryptogenic etiologies, and have not kept pace with recent discoveries of mutations in genes in key pathways of central nervous system development in patients with infantile spasms. Children with certain...

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Identifiers

PMID: 22114996
DOI: 10.1016/j.pediatrneurol.2011.08.010
PMCID: PMC3397192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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