Article

PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers

2019-03-18

Abstract excerpt

<h4>ABSTRACT</h4> While organ-confined PCa is mostly therapeutically manageable, metastatic progression of PCa remains an unmet clinical challenge. Resistance to anoikis, a form of cell death initiated by cell detachment from the surrounding extracellular matrix, is one of the cellular processes critical for PCa progression towards aggressive disease. Therefore, further understanding of anoikis regulation in PCa...

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Literature Corpus work: 90186365-cb1f-5d53-8808-a86af18850f3
DOI: 10.1101/581660

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