Article

Upregulation of <i>GREB1</i> in colorectal cancer ovarian metastases may be a potential therapeutic target

2025-09-03

Abstract excerpt

<h4>Introduction</h4> Classification of ovarian metastases (OM) in colorectal cancer (CRC) as peritoneal metastasis (PM) remains controversial. OM demonstrate resistance to systemic therapy, suggesting distinct molecular tumorigenesis. Gene expression profiling and transcriptomic analysis were performed to distinguish OM, PM, and primary CRC (pCRC) and identify potential therapeutic targets. <h4>Methods</h4> RNA...

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Literature Corpus work: 9004e1f3-3fab-5247-a95b-6cf638a62634
DOI: 10.1101/2025.08.31.673371

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