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Exploring the Role of Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease

14 Jun 2024

Abstract excerpt

Parkinson's disease (PD) is a prevalent neurodegenerative disorder among the elderly population. The pathogenesis of PD encompasses genetic alterations, environmental factors, and age-related neurodegenerative processes. Numerous studies have demonstrated that aberrant functioning of the ubiquitin-proteasome system (UPS) plays a crucial role in the initiation and progression of PD. Notably, E3 ubiquitin ligases...

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PMID: 38931449
DOI: 10.3390/ph17060782

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