Article

PPARγ/ETV2 Axis Regulates Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

2022-05-19

Abstract excerpt

<h4>ABSTRACT</h4> Endothelial-to-mesenchymal transition (EndoMT) plays an important role in pulmonary hypertension (PH). Also, the molecular mechanisms regulating EndoMT in PH remain to be defined. In this study, we first showed that reduced expression of the transcription factors ETV2 (ETS variant 2) and PPARγ (Peroxisome Proliferator-Activated Receptor gamma) along with reduced endothelial markers and increased...

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Literature Corpus work: 8fd61f92-d549-5f68-8f84-5fd5b4a2c9bd
DOI: 10.1101/2022.05.17.492293

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