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Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease

7 Feb 2022

Abstract excerpt

Endothelial-mesenchymal transition (EndoMT), a cellular differentiation process in which endothelial cells (ECs) lose their properties and differentiate into mesenchymal cells, has been observed not only during development but also in various pathological states in adults, including cancer progression and organ/tissue fibrosis. Transforming growth factor-β (TGF-β), an inflammation-related cytokine, has been shown...

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PMID: 35130955
DOI: 10.1186/s41232-021-00186-3

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