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Integrating Machine Learning-Enhanced Immunopeptidomics and SARS-CoV-2 Population-Scale Analyses Unveils Novel Antigenic Features for Next-Generation COVID-19 Vaccines

2024-02-12

Abstract excerpt

<title>Abstract</title> <p>Next-generation T-cell-directed vaccines for COVID-19 aim to induce durable T-cell immunity against circulating and future hypermutated SARS-CoV-2 variants. Mass Spectrometry (MS)-based immunopeptidomics holds promise for guiding vaccine design, but computational challenges impede the precise and unbiased identification of conserved T-cell epitopes crucial for vaccines against rapidly m...

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Literature Corpus work
8fd336a5-daf3-5063-9345-f3fa4d7e642c
DOI
10.21203/rs.3.rs-3914861/v1
Open publication

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Integrating Machine Learning-Enhanced Immunopeptidomics and SARS-CoV-2 Population-Scale Analyses Unveils Novel Antigenic Features for Next-Generation COVID-19 VaccinesDOI 10.21203/rs.3.rs-3914861/v1
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