Article

Bovine blastocyst development depends on threonine catabolism

2018-09-07

Abstract excerpt

<h4>ABSTRACT</h4> Increasing evidence suggests that pluripotency is a metabolically specialised state. In mouse, inner cell mass (ICM) cells and ICM-derived pluripotent stem cells (PSCs) critically depend on catabolising the amino acid threonine, while human PSCs require leucine, lysine, methionine or tryptophan. However, little is known about the specific amino acid requirements of putative pluripotent cells in...

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Literature Corpus work: 8fc6abe0-ab54-5581-9b94-4406c6a7a535
DOI: 10.1101/397562

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