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Article

Melatonin accelerates the developmental competence and telomere elongation in ovine SCNT embryos

21 Jul 2022

Abstract excerpt

SCNT embryos suffer from poor developmental competence (both in vitro and in vivo) due to various defects such as oxidative stress, incomplete epigenetic reprogramming, and flaws in telomere rejuvenation. It is very promising to ameliorate all these defects in SCNT embryos by supplementing the culture medium with a single compound. It has been demonstrated that melatonin, as a multitasking molecule, can improve...

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PMID: 35862346
DOI: 10.1371/journal.pone.0267598

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