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Genome-wide characterization of SARS-CoV-2 cytopathogenic proteins in the search of antiviral targets

2021-11-24

Abstract excerpt

Therapeutic inhibition of critical viral functions is important for curtailing coronavirus disease-2019 (COVID-19). We sought to identify antiviral targets through genome-wide characterization of SARS-CoV-2 proteins that are crucial for viral pathogenesis and that cause harmful cytopathic effects. All twenty-nine viral proteins were tested in a fission yeast cell-based system using inducible gene expression. Twelv...

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Literature Corpus work
8f0ceb2d-9e7d-5fd8-8ddf-77221370d689
DOI
10.1101/2021.11.23.469747
Open publication

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Genome-wide characterization of SARS-CoV-2 cytopathogenic proteins in the search of antiviral targetsDOI 10.1101/2021.11.23.469747
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