Article

Epigenetically inhibiting CYP3A5 modulates the migration and invasion of esophageal squamous cell carcinoma via ZEB2

2022-09-06

Abstract excerpt

<h4>Background: </h4> Aberrant suppression of cytochrome P450 3A5 (CYP3A5) is frequently observed in human esophageal squamous cell carcinoma (ESCC); however, its role and the epigenetic mechanism mediating transcriptional repression of CYP3A5 in ESCC remain poorly understood. <h4>Results: </h4>: Herein, we examined the expression and prognostic role of CYP3A5 in tumor tissues obtained from patients with ESCC. CYP...

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Literature Corpus work: 8ef56781-4df2-596e-a8e8-4baf24da83f4
DOI: 10.21203/rs.3.rs-2013301/v1

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