Article
Systematic cancer-testis gene expression analysis identified CDCA5 as a potential therapeutic target in esophageal squamous cell carcinoma
16 Jul 2019
Abstract excerpt
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies with poor prognosis. Cancer-testis genes (CTGs) have been vigorously pursued as targets for cancer immunotherapy, but the expressive patterns and functional roles of CTGs remain unclear in ESCC. METHODS: A systematic screening strategy was adopted to screen CTGs in ESCC by integrating multiple public databases and RNA...
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